Adam V Patterson Selected Research

azachloromethylbenzindoline

6/2006

Radiolytic and cellular reduction of a novel hypoxia-activated cobalt(III) prodrug of a chloromethylbenzindoline DNA minor groove alkylator.

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Adam V Patterson Research Topics

Disease

39	Neoplasms (Cancer) 02/2022 - 01/2002
35	Hypoxia (Hypoxemia) 02/2022 - 01/2003
4	Breast Neoplasms (Breast Cancer) 10/2020 - 09/2003
3	Disease Progression 03/2017 - 02/2014
3	Carcinoma (Carcinomatosis) 04/2013 - 10/2003
2	Necrosis 01/2022 - 01/2012
2	Hypersensitivity (Allergy) 10/2020 - 06/2009
2	Lung Neoplasms (Lung Cancer) 01/2020 - 12/2015
2	Hepatocellular Carcinoma (Hepatoma) 01/2019 - 01/2015
1	Colonic Neoplasms (Colon Cancer) 01/2022
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Prostatic Neoplasms (Prostate Cancer) 03/2018
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Precursor T-Cell Lymphoblastic Leukemia-Lymphoma (T-ALL) 03/2014
1	Small Cell Lung Carcinoma (Small Cell Lung Cancer) 07/2012
1	Insulinoma 07/2012

Drug/Important Bio-Agent (IBA)

40	ProdrugsIBA 02/2022 - 10/2003
15	PR-104AIBA 02/2022 - 07/2007
13	EnzymesIBA 01/2019 - 09/2003
11	Oxidoreductases (Dehydrogenase)IBA 11/2021 - 09/2003
11	PR-104IBA 01/2016 - 07/2007
9	DNA (Deoxyribonucleic Acid)IBA 01/2015 - 01/2004
8	Cytotoxins (Cytolysins)IBA 01/2019 - 10/2003
7	NitroreductasesIBA 02/2022 - 10/2009
7	NADPH-Ferrihemoprotein Reductase (Cytochrome P450 Reductase)IBA 10/2020 - 09/2003
6	Oxygen (Dioxygen)IBA 01/2022 - 06/2007
6	Tirapazamine (SR 4233)IBA 03/2010 - 01/2003
5	Biomarkers (Surrogate Marker)IBA 02/2019 - 05/2009
4	Phosphates (Orthophosphate)IBA 02/2022 - 09/2007
4	Pharmaceutical PreparationsIBA 01/2021 - 10/2003
4	EstersIBA 01/2019 - 09/2007
4	Proteins (Proteins, Gene)FDA Link 10/2014 - 10/2003
3	Antineoplastic Agents (Antineoplastics)IBA 12/2021 - 08/2005
3	tretazicarIBA 01/2021 - 10/2008
3	AminesIBA 01/2015 - 10/2009
3	Hydroxylamine (Hydroxylamine Hydrochloride)IBA 01/2015 - 07/2007
3	Aldo-Keto ReductasesIBA 01/2015 - 03/2010
3	CEN-209IBA 10/2014 - 12/2013
3	quinone (benzoquinone)IBA 12/2013 - 01/2002
2	SN33623IBA 01/2021 - 01/2019
2	Phosphotransferases (Kinase)IBA 01/2021 - 01/2019
2	4-nitroimidazoleIBA 01/2021 - 01/2019
2	PeptaibolsIBA 01/2020 - 01/2020
2	azomycinIBA 01/2019 - 03/2012
2	OxidesIBA 10/2014 - 02/2014
2	Nitro CompoundsIBA 02/2014 - 10/2009
2	Mechlorethamine (Nitrogen Mustard)FDA Link 03/2010 - 07/2007
2	Alkylating AgentsIBA 10/2009 - 06/2006
2	Mitomycin (Mitomycin-C)FDA LinkGeneric 06/2009 - 09/2003
1	vadimezanIBA 01/2022
1	A-Form DNA (A-DNA)IBA 12/2021
1	Cytochrome P-450 Enzyme System (Cytochrome P450)IBA 11/2021
1	tylophorineIBA 06/2021
1	antofineIBA 06/2021
1	Biological ProductsIBA 06/2021
1	Hydroxyl RadicalIBA 10/2020
1	CopperIBA 10/2020
1	LipidsIBA 01/2020
1	antineoplaston A10 (A 10)IBA 01/2020
1	culicinin DIBA 01/2020
1	Amino Acids FDA Link 01/2020
1	futibatinibIBA 01/2019
1	Fibroblast Growth Factors (Fibroblast Growth Factor)IBA 01/2019
1	AmidesIBA 01/2019
1	Type 4 Fibroblast Growth Factor ReceptorIBA 01/2019
1	ElementsIBA 03/2018
1	Carrier Proteins (Binding Protein)IBA 03/2018
1	SN34507IBA 01/2016
1	SN35539IBA 01/2016
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 12/2015
1	Gefitinib (Iressa)FDA Link 12/2015
1	Sorafenib (BAY 43-9006)FDA Link 01/2015
1	TriazinesIBA 06/2014
1	Messenger RNA (mRNA)IBA 03/2014
1	SN 34037IBA 03/2014
1	Coordination ComplexesIBA 02/2014
1	QuinonesIBA 02/2014
1	Zinc Finger NucleasesIBA 12/2013
1	isophosphamide mustard (IPAM)IBA 03/2012
1	NucleotidesIBA 03/2012
1	TH 302IBA 03/2012
1	Carbonic Anhydrase IXIBA 01/2012
1	Caspase 3 (Caspase-3)IBA 01/2012
1	Monoclonal AntibodiesIBA 01/2012
1	Naproxen (Naprosyn)FDA LinkGeneric 03/2011
1	3-amino-1,2,4-benzotriazineIBA 03/2010
1	Adenine FDA LinkGeneric 10/2009
1	Chlorambucil (Leukeran)FDA Link 06/2009
1	Cytosine DeaminaseIBA 10/2008
1	Fluorouracil (Carac)FDA LinkGeneric 10/2008
1	Flucytosine (Ancobon)FDA Link 10/2008
1	nitromide (Unistat)IBA 07/2007
1	Docetaxel (Taxotere)FDA Link 07/2007
1	Gemcitabine FDA Link 07/2007

Therapy/Procedure

14	Therapeutics 01/2021 - 08/2005
7	Drug Therapy (Chemotherapy) 12/2015 - 01/2002
6	Radiotherapy 02/2014 - 01/2004
2	Immunotherapy 01/2022 - 01/2021
2	Aftercare (After-Treatment) 10/2007 - 07/2007
1	Castration 03/2018